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Fire & Flower Holdings Corp. Opens the Market

Vlad Poptamas

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Fire & Flower Holdings Corp. Opens the Market
Reading Time: 1 minute

 

Trevor Fencott, Chief Executive Officer, Fire & Flower Holdings Corp. (FAF), joined Dani Lipkin, Innovation Sector Head, Capital Formation, Toronto Stock Exchange and TSX Venture Exchange, to open the market. Fire & Flower Holdings Corp., through its wholly-owned subsidiary Fire & Flower, is an independent retail chain that offers cannabis products and accessories such as cannabis, cannabis oil, accessories and apparel to the adult-use market. Fire & Flower Holdings Corp. graduated and commenced trading on Toronto Stock Exchange on August 7, 2019.

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Cannabis Can Treat Epileptic Seizures

Alexandru Marginean

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Photo by Get Budding on Unsplash
Reading Time: 3 minutes

Cannabis has been used for millennia to treat many conditions. It has long been known that cannabis can help with pain, depression, and was even used in ancient China as an anesthetic for surgery.

It has also been recognized millennia ago as a potential treatment for epilepsy. However, it wasn’t until recently that we have had the scientific studies to back those beliefs up.

It all began with a girl named Charlotte Figi. Charlotte has a rare form of epilepsy known as Dravet Syndrome. At just three months old, Charlotte had her first seizure. The seizure lasted half an hour. It only got worse from there; as Charlotte got older, the number and severity of her daily seizures increased. Some of the seizures lasted up to four hours.

By the time that Charlotte was two, she began showing signs of cognitive decline and displaying signs of autistic behavior. She had aggressive outbursts, would injure herself, and was reluctant to make eye contact. At one time, Charlotte was having up to three hundred grand mal seizures a week, despite being on heavy duty anti-seizure medications. At times, her heart stopped during the seizures. Charlotte’s parents and doctors eventually put her into a medically induced coma to allow her to recuperate. They even signed a do-not-resuscitate order in the event that something went horribly wrong.

Then, Charlotte’s grandfather started reading several success stories from parents who were using cannabis to treat their children’s seizures. Another boy with Dravet’s Syndrome and his story stood out. Charlotte’s doctors had said that they had done all they could. In desperation, her parents got a hold of some R4 cannabis extract oil for Charlotte. A miracle occurred. Charlotte went from 300 seizures a week to zero seizures during her first week of treatment. Seeing that the cannabis treatment was helping, Charlotte’s parents reached out to the Stanley Brothers, who run medical marijuana farms and dispensaries in Colorado. They created Charlotte’s Web, a hybrid strain of medical marijuana, which contained a 30:1 mixture of CBD to THC.

After Charlotte’s success story came a number of others. All from parents whose children were helped by Charlotte’s Web and other high-CBD cannabis treatments. Anecdotal stories are one thing, but is there scientific evidence? The answer to that is yes.

In 2016, Orrin Devinsky, a neurologist at New York University Langone Medical Center and colleagues across multiple research centers published the results from a study of a cannabis-based drug for treatment-resistant epilepsy in the journal Lancet Neurology. 162 patients were treated with an extract of 99% cannabidiol (CBD) and monitored them for 12 weeks. The treatment was given in conjunction with existing medications.

The results were more than promising. The treatment resulted in the reduction of motor seizures that was comparable to similar drugs. 2% of patients reported being seizure- free. The trial led by Devinsky was the most robust assessment of CBD’s effect on epilepsy. Unfortunately, these trials were open trials and had no controlled factors.

However, more recently, the Food and Drug Administration approved a highly purified oral preparation of CBD. In the open label expanded access programs as well as placebo-controlled trials, there was a significant improvement in seizure frequency when compared to the placebo patients with Dravet Syndrome and Lennox-Gastaut Syndrome. The drug that has been approved by the FDA is the prescription medication known as Epidolex.

The results from the gold-standard studies of Epidolex were extremely promising. In the group receiving 20 mg of CBD twice daily, the occurrence of seizures dropped 41.9%. In those receiving the 10 mg dose, seizures dropped by 37.2%. In the placebo group, seizures dropped by 17.2%. Like with all other medications, even treatment with CBD oil has its side effects. For the most part, the side effects are well tolerated and only a few patients experienced side effects serious enough to stop taking the medication. The most commonly reported side effects were sedation, decreased appetite, and diarrhea.

When it comes to the legality of CBD treatments, especially those not approved by the FDA, there is good news. The passage of the 2018 Farm Bill hemp and hemp-derived substances are exempt from the Controlled Substances Act. This includes CBD oil, which can be purchased at places like TheAmsterdam. Even though it has been legalized, it is important that any parent or patient speak with their doctors before beginning any treatment.

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Addressing THC Detox Myths and Facts

Alexandru Marginean

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Photo by Sharon McCutcheon on Unsplash
Reading Time: 4 minutes

Cannabis is a popular drug. Slowly it’s becoming more socially acceptable for people of all ages. But that doesn’t mean marijuana is safe, especially in terms of detoxing.

There are several myths concerning THC detox; so much so that many users perform it without any health concerns.

Below is a list of THC detox myths and facts to consider. But before that, here’s a brief explanation of what detoxing is.

 

THC Detox: What Is Detoxing?

Detox is the practice of refraining from consuming a substance to cleanse your system of any trace, which in this case is a Tetrahydrocannabinol (THC) cleanse.

As you abstain from consuming marijuana, your body is able to flush THC out of the system. While the process could be easy for some, others may find it difficult; it mostly depends on how heavily one has been consuming marijuana and whether or not they were doing it for medical purposes.

Some of the side effects of THC detox are as follows:

  • Anxiety
  • Headaches
  • Insomnia
  • Irritability
  • Loss of appetite, etc.

Usually, it takes up to 15 days before your system is clean—that is if you’re an occasional user. However, reports suggest that heavy users should abstain from pot usage for about 77 days. Now, if you have a drug test next week at the office, it’s likely to try some unusual things to cheat the test—this is where we cue in.

Here are some common myths and facts regarding THC detox you should know about.

Myth no. 1: All It Takes Is an Ungodly Amount of Water

False. Also referred to as “dilution” or ‘flushing,” this myth indicates that drinking a lot of water dilutes your urine just enough to make THC completely undetectable.

Fact: It’s Dangerous

Excessive water consumption is dangerous and may cause hyperhydration, which, in turn, can also lead to electrolyte disorders. When you dilute urine excessively, it’ll have a decreased specific creatinine and gravity level—both of these are identified during the drug testing process.

 

Myth no. 2: Fake Urine is Key

No. You will find a bunch of firms selling synthetic urine online. As far as stories go, some people have claimed to use chicken broth as a substitute, even though it lacks all of the chemical properties of urine.

Fact: Lab Test Are No Joke

It would be silly to assume that a highly trained lab specialist will be tricked by chicken noodle soup broth. The chemical properties and analysis are sure to catch you, if not the smell. And it’s the same story with fake urine.

 

Myth no. 3: Natural Diuretics Help to Flush Toxins Out of the System

Diuretics are essentially substances that boost urine production, as well as output. Some of the most popular diuretics are tea, coffee, cranberry juice, beer, and pretty much any beverages with caffeine. Furthermore, there are medications like Modil or Lasix that claim to work.

Fact: They Do Not Eliminate Toxins

While diuretics can make you urinate, they don’t eliminate THC. Of course, they can remove toxins from your body and reduce metabolites’ concentration in urine. However, the consumption of diuretic is similar to drinking plenty of water concerning detox purposes.

 

Myth no. 4: Intense Exercise Is the Answer

THC is stored in the fat cells of our body. Therefore, the more body fat one has, the longer it will take to detox. Solid exercise like resistance training and cardio can burn fat and boost your metabolism.

Fact: It’s Not a Short-Term Fix

You must exercise on a regular basis to stay healthy, fit, and make sure your weight is under control. But it’s by no means a magic “THC detox getaway card.” Exercising regularly may help to pass the test, but keep in mind that it’s a slow process; not one that can be achieved overnight.

 

Myth no. 5: “I am only a passive smoker.”

When everything else fails, some people claim to be in a room full of heavy smokers; hence they did not pass the drug test. As interesting as it may sound, the world doesn’t work that way.

Fact: You Cannot Inhale Smoke From Other People’s Bong and Use It As Defense

All drug tests have a certain cut-off level. A urinalysis for cannabis, in most cases, has its cut-off point at 50 ng per milliliter, and you simply cannot reach that point through passive inhalation.

 

Wrapping Up

So, the time has come for a THC detox. Maybe you have a drug test coming up or decided to take a tolerance break and want to cleanse your body before starting anew. Regardless of the reason, we hope you’ll consider the myths and facts concerning THC detox mentioned in this article. Also, it’s always good to consult with a doctor beforehand.

 

About the author: Kathrin Garner is an enthusiastic journalist and writes article on social issues. As an activist, she takes part in NCSM program, which is a discussion platform on the relevant cannabis topics. So, if you want to know how to detox from weed, feel free to contact her. Also, she is a volunteer at Marijuana Detox.  She searches for current issues, and writes about it to a wide range of readers.

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Marijuana Detox: The Main Things You Should Know

Alexandru Marginean

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Photo by Rick Proctor on Unsplash
Reading Time: 3 minutes

As more states move to end marijuana criminalization, Americans’ support for legalizing and regulating cannabis has only grown stronger.

60% of Americans support cannabis legalization, according to The Hill. While some are assessing the medicinal value it possesses, others are seeking ways to rid the toxins of their bodies.

Today, we’re going to discuss everything you need to know about marijuana detox and how it works.

 

What Does Cannabis Leave Behind?

As you smoke pot, you’re able to feel instant effects. However, even when the effects are no longer present, cannabis metabolites remain. What this means is that the plant’s chemical remnants stay within your system.

These chemical remnants are commonly known as cannabinoids. They are easily detected in hair, saliva, blood, urine, and fingernails.

 

Drug Tests: What Do They Look For?

Usually, drug tests identify THC presence in your system. A urine test is pretty common in that regard because it’s easier to collect and THC remains identifiable for a longer period in urine compared to elsewhere.

The key metabolite these drug tests determine is known as THC-COOH, which is stored in our body fat.

 

Detox Remedies: How Do They Work?

The majority of cannabis detoxes look to flush any traceable THC out of the body. These kits may include drinks, mouthwashes, shampoos, capsules, and chewable tablets—all of which help to pass saliva tests.

If drug tests are your primary concern, you should know that detoxes can come with additional effects (e.g., the urine sample may look suspicious).

Teas and cleanses can decrease THC levels via their known diuretic properties. What they do is make you pee a lot—this washes out your kidneys. The flushing of kidneys can potentially reduce the specific density or gravity of your urine, and a decreased specific gravity means contamination on your test. Therefore, you’ll be discounted.

Furthermore, teas and cleanses can alter the amounts of creatinine in your urine, which is another measure most drug tests tend to look at. Unusual creatinine levels may indicate contamination, meaning the tester can assume you’ve attempted to cheat your test.

 

THC: How Long Does It Stick Around?

Tetrahydrocannabinol (THC) can be identified in your urine, blood, and fat cells. The number of days THC remains identifiable in your body depends on various factors, including your:

  • Exercise routine
  • Eating habits and metabolism
  • Quantity and frequency of cannabis use, and
  • The percentage of body fat

Due to the above-mentioned factors, there’s no standard identification time. However, some estimate THC can linger in your system for anywhere between 2 to 77 days (or even more).

THC remains detectable in blood for around 7 days, depending solely on how often you use cannabis. For instance, someone who smokes pot on a daily basis will likely carry cannabis metabolites for a longer period than someone who does so occasionally.

 

Wrapping Up

As of this year, 33 states and the District of Columbia have passed laws broadly legalizing cannabis in some form. However, regardless of the legality, it’s crucial to note that cannabis carries certain health risks with it. We suggest you know the potential risks of using marijuana before deciding to consume it.

 

About the author: Kathrin Garner is an enthusiastic journalist and writes article on social issues. As an activist, she takes part in NCSM program, which is a discussion platform on the relevant cannabis topics. So, if you want to know how to detox from weed, feel free to contact her. Also, she is a volunteer at Marijuana Detox.  She searches for current issues, and writes about it to a wide range of readers.

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