Orbisresearch.com has published “Global Contract Development and Manufacturing Organizations (CDMOs) Market Report, History and Forecast 2014-2025, Breakdown Data by Manufacturers, Key Regions, Types and Application” research study to its database.
Dallas, Texas, Aug. 14, 2019 (GLOBE NEWSWIRE) — The CDMO industry started out decades ago as a niche service, offering additional manufacturing capacity or specialty services to pharmaceutical companies. The rise of the CDMOs was fueled by failure stories in the pharmaceutical industry. In the past, pharmaceutical companies often installed dedicated manufacturing capacities for innovative drugs in development, only to see them fail during phase III of clinical research trials. Thus, the additional manufacturing capacity for the specific drugs was no longer needed.
Contract development and manufacturing organizations are fetching lucrative returns at the backdrop of growing initiatives by pharmaceutical companies to outsource large scale drug development as well as clinical trials, in a bid to limit hefty operational investments. Additionally, delegating such resource intensive activities have played vital roles in exploiting superlative talent pools and high end professional expertise to materialize vital clinical trials pertaining to novel drug discovery. On the back of aforementioned factors, the global contract development and manufacturing organizations market is poised to remain thoroughly lucrative in the coming years, opines Orbis Research in its recently collated report offering titled, ‘Global Contract Development and Manufacturing Organizations (CDMOs) Market History and Forecast 2014-25’ included in its growing online data archive.
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Key players covered in the report are Recipharm, AMRI3, Patheon, Aenova, Catalent, Amatsigroup, WuXi PharmaTech, Strides Shasun, Piramal, and Siegfried
Burgeoning advances in pharmaceutical and biotechnology companies and their ongoing efforts to diversify drug potential and new chemical entities catering to accelerating disease conditions and subsequent fatality have lent ample growth thrust to global contract development and manufacturing organizations market. Additionally, favorable cooperation on the part of FDA in the form of remunerative fund allocation to leverage palpable progress in clinical researches have encouraged pharmaceutical companies to establish long term commitments with various contract manufacturers to fasten drug manufacturing across regions.
With surged reliance on contract development and manufacturing entities, drug manufacturers incur palpable benefits such as marked reduction in operational expenditure. This has reflected favorably on revenue sustainability, thus instrumenting substantial momentum in rapid adoption and eventual growth in global contract development and manufacturing market worldwide.
Escalating Rare Disease Occurrence Fuels Fresh FDA Funds
With a significantly large aging population, the pharmaceutical industry is witnessing a sharp paradigm shift towards development of new chemical entities (NCE) and drugs favoring prompt medical aid to a rapidly thwarting rare disease occurrence and subsequent mortality. To favor this growing quest for advanced drug formulation, the US FDA has recently affirmed its initiative to allocate a total of 12 updated grants worth a total of $18m exclusively dedicated towards rare disease clinical trials.
Insufficient Medical Literature and Research Participants Remain Operational Hurdles
Orphan disease and rare diseases have in recent years garnered a lot of attention owing to substantially high terminal outcome. this has led to spearheading dedicated initiatives towards specific drug discovery to eradicate and effectively manage orphan diseases.
However, orphan drug development is a time consuming investment with low potency to fetch desirable research outcome, especially with small population participants. Hence, pharma companies are of late highly motivated to render various orphan drug clinical researches to professional contract development and manufacturing organizations (CDMO) who are equipped with sophisticated technology as well as skilled manpower to attain path breaking advances in novel drug making, paving way for fresh deals amongst biotech and contract development and manufacturing entities.
China Based Biotech CANbridge Allies with CDMO, BioExcellence for Oncology
Industry forerunners in drug development are rapidly establishing partnership deals with promising contract development and manufacturing organizations to further register substantial progress in drug development for wide spread categories of rare diseases. To cite an instance, the CDMO offshoot of pharmaceutical behemoth, Boehringer Ingelheim, BioXcellence has been chosen to provide CANbridge Life Sciences, a China based biotechnology company with relevant clinical trial resources targeted for phase III clinical trials for a novel drug candidate for esophageal therapeutics.
This report studies the Contract Development and Manufacturing Organizations (CDMOs? market size (value and volume) by players, regions, product types and end industries, history data 2014-2018 and forecast data 2019-2025; This report also studies the global market competition landscape, market drivers and trends, opportunities and challenges, risks and entry barriers, sales channels, distributors and Porter’s Five Forces Analysis.
Geographically, this report is segmented into several key regions, with sales, revenue, market share and growth Rate of Contract Development and Manufacturing Organizations (CDMOs? in these regions, from 2014 to 2025, covering
North America (United States, Canada and Mexico)
Europe (Germany, UK, France, Italy, Russia and Turkey etc.)
Asia-Pacific (China, Japan, Korea, India, Australia, Indonesia, Thailand, Philippines, Malaysia and Vietnam)
South America (Brazil etc.)
Middle East and Africa (Egypt and GCC Countries)
Browse the full report@https://www.orbisresearch.com/reports/index/global-contract-development-and-manufacturing-organizations-cdmos-market-report-history-and-forecast-2014-2025-breakdown-data-by-manufacturers-key-regions-types-and-application
By the product type, the market is primarily split into Development, API production, and Formulation
By the end users/application, this report covers the following segments Pharmaceutical Industry, Biotechnology, and Other
This report includes the estimation of market size for value (million USD) and volume (K Units). Both top-down and bottom-up approaches have been used to estimate and validate the market size of Contract Development and Manufacturing Organizations (CDMOs? market, to estimate the size of various other dependent submarkets in the overall market. Key players in the market have been identified through secondary research, and their market shares have been determined through primary and secondary research. All percentage shares, splits, and breakdowns have been determined using secondary sources and verified primary sources.
For the data information by region, company, type and application, 2018 is considered as the base year. Whenever data information was unavailable for the base year, the prior year has been considered.
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Major points from Table of Contents:
1 Contract Development and Manufacturing Organizations (CDMOs? Market Overview
2 Global Contract Development and Manufacturing Organizations (CDMOs? Market Competition by Company
3 Contract Development and Manufacturing Organizations (CDMOs? Company Profiles and Sales Data
4 Contract Development and Manufacturing Organizations (CDMOs? Market Status and Outlook by Regions
5 Contract Development and Manufacturing Organizations (CDMOs? Application
6 Global Contract Development and Manufacturing Organizations (CDMOs? Market Forecast
7 Contract Development and Manufacturing Organizations (CDMOs? Upstream Raw Materials
8 Marketing Strategy Analysis, Distributors
9 Research Findings and Conclusion
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ShiftPixy, Inc. Reports Fiscal 2019 Results
IRVINE, Calif., Dec. 13, 2019 (GLOBE NEWSWIRE) — ShiftPixy, Inc. (NASDAQ: PIXY), a California-based staffing enterprise that designs, manages, and sells access to a disruptive, revolutionary platform that facilitates employment in the rapidly growing Gig Economy, today announced operating results for the year ended August 31, 2019 (“2019”).
2019 Financial Highlights
- Earnings per share improved to $0.57 in 2019 compared to $0.58 for 2018.
- Gross billings grew 59% to $353 million, compared to $222 million for 2018. Q4 billings exceeded $100 million for the first quarter in our history at $105 million for an exit annualized billings rate of over $420 million.
- Revenues increased 53% to $53 million, compared to $35 million for 2018.
- Gross profit was $12.4 million, increasing 125% over 2018 gross profit of $5.5 million due to improving margins and workers compensation cost savings. Gross profit per worksite employee improved to $1,200 for 2019 from $800 for 2018.
- Loss from Operations improved to $9.7 million from $11.6 million in 2018.
- EBITDAS Loss (Operating Loss excluding depreciation and share-based compensation) improved to $8.3 million for 2019 from $11.0 million for 2018 due to improved margins and reduced spending on our mobile application, offset by increased operations costs.
- Investment in our mobile application and technology solution deployment decreased to $4.9 million in 2019 from $7.5 million in 2018 due to reduced costs relating to movement to our new in-sourced development team. Total Human Resource Information System (HRIS) and mobile application investment is $15.5 million to date.
2019 Operational highlights
- The number of employees billed during the year and retained in our employee HRIS exceeded 25,000.
- The active number of worksite employees billed increased to 13,100 at August 31, 2019, a 54% increase, from 8,500 at August 31, 2018.
- Average gross billings per worksite employee increased by 4.3% to $33,600 in 2019 from $32,200 in 2018
- Average operating support costs per billed worksite employee improved in 2019. We have staffed to manage up to 50,000 active worksite employees with our current corporate overhead.
- Our dispute with our outsourced software development partner delayed our HRIS and mobile application launch in 2019 and necessitated our move towards in-house development.
“We continue to see strong growth in our legacy business which has driven top line expansion and improvement in our operating metrics, including gross billings and gross profits for 2019,” stated Chief Executive Officer, Scott Absher. ”Delays in the launch of our mobile application solution are now behind us and the project is now back on track and well received by our initial launch customers. We believe it will support revenue growth in 2020 from both significantly higher worksite employee counts and added technology features. The reception from our target customers has been phenomenal and we expect to see a significant increase in our business activity levels as we move into calendar 2020 and continue our focus on creating long-term shareholder value.”
ShiftPixy is a disruptive human capital services enterprise, revolutionizing employment in the Gig Economy by delivering a next-gen platform for workforce management that helps businesses with shift-based employees navigate regulatory mandates, minimize administrative burdens and better connect with a ready-for-hire workforce. With expertise rooted in management’s nearly 25 years of workers’ compensation and compliance programs experience, ShiftPixy adds a needed layer for addressing compliance and continued demands for equitable employment practices in the growing Gig Economy. ShiftPixy’s complete HCM ecosystem is designed to manage regulatory requirements and compliance in such required areas as paid time off (PTO) laws, insurance and workers’ compensation, minimum wage increases, and the Affordable Care Act (ACA) compliance.
ShiftPixy Cautionary Statement
The information provided in this release includes forward-looking statements, the achievement or success of which involves risks, uncertainties, and assumptions. Although such forward-looking statements are based upon what management of the Company believes are reasonable assumptions, there can be no assurance that forward-looking statements will prove to be accurate. If any of the risks or uncertainties, including those set forth below, materialize or if any of the assumptions proves incorrect, the results of ShiftPixy, Inc., could differ materially from the results expressed or implied by the forward-looking statements we make. The risks and uncertainties include, but are not limited to, risks associated with the nature of our business model; our ability to execute the Company’s vision and growth strategy; our ability to attract and retain clients; our ability to assess and manage risks; changes in the law that affect our business and our ability to respond to such changes and incorporate them into our business model, as necessary; our ability to insure against and otherwise effectively manage risks that affect our business; competition; reliance on third-party systems and software; our ability to protect and maintain our intellectual property; and general developments in the economy and financial markets. Statements made in connection with any guidance may refer to financial statements that have not been reviewed or audited. The Company undertakes no obligation to update forward-looking statements if circumstances or management’s estimates or opinions should change, except as required by applicable securities laws. The information in this press release shall not be deemed to be “filed” for the purpose of Section 18 of the Securities Exchange Act of 1934, as amended, or otherwise subject to the liabilities of that section, and will not be deemed an admission as to the materiality of any information that is required to be disclosed solely by Regulation FD. Further information on these and other factors that could affect the financial results of ShiftPixy, Inc., is included in the filings on Forms 1-A and 10-Q and in other filings we make with the Securities and Exchange Commission from time to time. These documents are available on the “SEC Filings” subsection of the “Investor Information” section of our website at https://ir.shiftpixy.com/financial-information/sec-filings.
Consistent with the SEC’s April 2013 guidance on using social media outlets like Facebook and Twitter to make corporate disclosures and announce key information in compliance with Regulation FD, ShiftPixy is alerting investors and other members of the general public that ShiftPixy will provide updates on operations and progress required to be disclosed under Regulation FD through its social media on Facebook, Twitter, LinkedIn and YouTube. Investors, potential investors, shareholders and individuals interested in our Company are encouraged to keep informed by following us on Facebook, Twitter, LinkedIn and YouTube.
Consolidated Balance Sheets
|Unbilled accounts receivable||9,478,000||6,193,000|
|Other current assets||244,000||259,000|
|Total current assets||14,031,000||10,447,000|
|Fixed assets, net||3,360,000||3,032,000|
|Deposits- workers’ compensation||6,281,000||2,202,000|
|Deposits and other assets||124,000||121,000|
|LIABILITIES AND STOCKHOLDERS’ DEFICIT|
|Accrued payroll and related liabilities||16,412,000||9,477,000|
|Convertible Notes, Net||3,351,000||6,171,000|
|Accrued workers’ compensation costs||1,957,000||305,000|
|Default penalties accrual||1,800,000||3,500,000|
|Other current liabilities||1,850,000||1,956,000|
|Total current liabilities||32,187,000||22,656,000|
|Accrued workers’ compensation costs||4,379,000||901,000|
|Commitments and contingencies|
|Preferred stock, 50,000,000 authorized shares; $0.0001 par value; no shares issued and outstanding||–||–|
|Common stock, 750,000,000 authorized shares; $0.0001 par value; 36,281,894 and 28,851,787 shares issued as of August 31, 2019 and 2018, respectively||4,000||3,000|
|Additional paid-in capital||32,501,000||18,465,000|
|Treasury stock, at cost – 558,132 shares and no shares as of August 31, 2019 and 2018, respectively||(325,000||)||–|
|Total stockholders’ deficit||(12,770,000||)||(7,755,000||)|
|Total liabilities and stockholders’ deficit||$||23,796,000||$||15,802,000|
Consolidated Statements of Operations
|For the Years Ended|
|Revenues (gross billings of $352.6 million and $222.4 million (unaudited) less worksite employee payroll cost of $299.2 million and $187.5 million, (unaudited) respectively)||$||53,436,000||$||34,959,000|
|Cost of revenue||41,046,000||29,458,000|
|Salaries, wages and payroll taxes||7,702,000||5,383,000|
|Share-based compensation – general and administrative||632,000||363,000|
|Marketing and advertising||1,208,000||547,000|
|General and administrative||3,823,000||3,005,000|
|Depreciation and amortization||839,000||274,000|
|Total operating expenses||22,063,000||17,072,000|
|Other income (expense)|
|Loss on debt extinguishment||(3,927,000||)||–|
|Change in fair value of derivative||2,569,000||–|
|Gain (Loss) associated with note defaults, net||811,000||(3,500,000||)|
|Total Other income (expense)||(9,054,000||)||(5,251,000||)|
|Net loss per common share|
|Basic and diluted||$||(0.57||)||$||(0.58||)|
|Weighted average number of common shares|
|Basic and diluted||32,708,800||28,810,103|
Ziyen Energy Announces the Acquisition of Non-Producing Minerals in Saxet Field, Nueces County, Texas in Exchange for 930,000 ZiyenCoins
SAN DIEGO, Dec. 13, 2019 (GLOBE NEWSWIRE) — Ziyen Energy has announced they have acquired the minerals at the Douglas Prospect, Saxet Field in Nueces County, Texas in exchange for 930,000 ZiyenCoins.
The Douglas Prospect, covers 83.19 gross acres, 15.6 mineral acres, and includes a recently drilled shut in oil well. The Douglas Prospect is in the Saxet Oil Field which has produced over 100,000,000 barrels of oil from approximately 40 separate reservoirs. The field was developed in the late 1930’s producing an approximate 17,000 barrels of oil per day.
Alastair Caithness, CEO, stated
“This is our third transaction in ZiyenCoin, and the first acquisition in owning the mineral rights. This will provide Ziyen Energy with a long-term asset for the company, as unlike leasing the property the company now owns the minerals indefinitely in a Texas oil field which has produced over 100 million barrels of oil. As we make every new transaction in ZiyenCoin we are starting to set a precedence on the pricing of each oil asset with our digital energy token.”
Learn more about Ziyen Inc. and ZiyenCoin by reading our 2019 Ziyen Inc. Corporate Overview.
If you would like a copy of ZiyenCoin’s Security Token Offering (STO), then please email email@example.com or visit www.ziyen.com for more information.
About Ziyen Energy:
Ziyen Energy. is a technology-driven energy company incorporated in the State of Wyoming, U.S.A. in April 2016. Originally formed as a software company providing information on the oil, gas, power and energy sectors, Ziyen specializes on business information, contracts, news and information by developing cutting edge procurement and supply chain software to provide clients with intelligence on industry specific government and private contracts. In addition, Ziyen Energy currently owns interests in oil assets based in Texas and the Illinois Basin, which covers Illinois, Indiana and Kentucky. The equity of Ziyen Energy has been tokenized and issued as ZiyenCoin which is offered for sale as a Security Token pursuant to SEC Rule 506(c) of Regulation D.
For more information visit www.ziyen.com
Forward Looking Statements:
Certain statements in this press release including, but not limited to, statements related to anticipated commencement of commercial production, targeted pricing, performance goals, and statements that otherwise relate to future periods are forward-looking statements. These statements involve risks and uncertainties, which are described in more detail in reports filed with the SEC. Forward-looking statements are made and based on information available to the company on the date of this press release. Ziyen Inc. assumes no obligation to update the information in this press release.
AE Ventures to Invest in Four new Blockchain Startups
MALTA, Dec. 13, 2019 (GLOBE NEWSWIRE) — (via Blockchain Wire) — AE Ventures, an investment company that provides initial funding, acceleration, and advisory support to blockchain projects, today announced four new Investments in Blockchain Startups as a part of its leading global blockchain accelerator Starfleet. The company is continuing to support the blockchain ecosystem investing in the most promising projects in this area despite the crypto market’s long standing problems. Four winning startups: Assetify, Cannomy, King Football, and Smart Credit, will each receive up to $100,000 USD in venture investment as well as six months of acceleration including support in the field of technology, business development, marketing and legal affairs from the AE Ventures team. Most importantly, they will retain access to Starfleet’s solid mentorship network, knowledge base, and expertise as part of the accelerator.
Situated in Malta – the well-known blockchain island, the third edition of the Starfleet accelerator program drew global coverage, attracting hundreds of startups from all over the world. The accelerator program is also streamed worldwide. Microsoft Innovation Center, Malta is a leading partner and host of the program’s third edition. Thanks to this partnership the startups would have further opportunity to incorporate in Malta. Additionally, Starfleet accelerator will start its first program in Bangalore, India, next year– thus expanding the scope of its activities.
“Starfleet Malta enables us to leverage our broad experience in developing blockchain projects, the strong expertise of our mentors and the support of the fast-growing blockchain ecosystem to welcome innovative blockchain companies into the AE Ventures family,” said Nikola Stojanow, CEO of AE Ventures. “With these new investments, we’re really looking forward to joining forces with promising startup teams to showcase the full potential of blockchain technologies that are changing the world.”
“At Microsoft, we believe that technology can empower all organizations and all people to achieve more; and that is exactly what we are doing with our MIC partners and AE Ventures,” said Vangelis Morfis, Microsoft’s M&O Lead for Greece, Cyprus, Malta. “Our partnership is promoting technology in Malta to help shape a better future for all. We are very proud to reward the work done by these start-ups in the areas of innovative technologies, such as Blockchain, and we commit to do even more in the coming months!”
The four new teams backed by Starfleet accelerator are:
Assetify, a b2b platform for crypto-backed loans, enabling lending institutions to provide credits using digital assets as collateral. The platform automates the relations between the user of the loan and the lender, creating multi-signature wallets. This is much cheaper and less risky. The company already has two paying customers — one bank in Switzerland and one lander in Bulgaria.
Cannomy, a pioneer of the cannabis economy, combining the benefits of promising blockchain technologies with the fast-growing cannabis ecosystem. The team is using Distributed Ledger Technology (DLT) to source the funding of new ventures in this field and facilitate their operations and manage shareholders.
King Football is using chips and æternity blockchain to help football fans track easily items and identify if they are fake or original. Building on this functionality, the team is creating a social platform allowing fans to receive personalized messages from football stars as well as to trade original items, creating a big secondary market. The popular Bulgarian football player Dimitar Berbatov is also involved in the project and 14 series of its painted by himself items are already live on æternity blockchain.
SmartCredit is aiming to democratize the lending industry, using transferable tokenized credit, and thus helping every lender to become a bank. This huge industry is responsible for 90% of the money available today and its decentralization will bring significant new advantages. The platform will create 2-click consumer credits (money on demand) for the borrower and tools like credit tokenization, credit transferability and interest-bearing to the holder.
The four teams were selected out of ten startups who pitched for investment on the Demo Day, which was held on December 12, 2019 in Microsoft Innovation Center, Malta and broadcasted live worldwide.
About AE Ventures
AE Ventures is an investment company providing initial funding, acceleration and advisory support to blockchain projects. The company also runs æternity Starfleet – a full-service global acceleration program for seed-stage startups utilizing blockchain. For more information, please visit www.aeventures.io and www.aeternitystarfleet.com
æternity is a public, open-source, blockchain platform offering means for a decentralized future realized by a global community. Blockchain inherently has the disruptive potential to support distributed wealth and transparency in power structures. æternity aims to solve problems of scalability, security, be more economical, and user-friendly when it comes to accessing the smart contracts on the network. For more information, please visit www.aeternity.com
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