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Children’s Hospital Los Angeles Has Treated 14 Patients With Retinal Degeneration Using Gene Therapy

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LOS ANGELES–(BUSINESS WIRE)–More than a year after becoming one of the first medical institutions nationally to complete a revolutionary gene replacement surgery to restore vision in patients with retinal degeneration, surgeons at The Vision Center at Children’s Hospital Los Angeles (CHLA) have successfully completed the procedure on an additional 13 patients.

The outcomes of two of those patients, San Diego residents Monroe Le, 6, and Heather Hodlin, 25, were chronicled on the recent ABC News Nightline episode, “Miracle of Sight.”

Photos of Monroe and Heather are available upon request at media@chla.usc.edu

“We have found that using gene therapy to treat this condition can be life-changing for children under the age of 10,” explains CHLA surgeon Aaron Nagiel, MD, PhD. “While they are not going to have normal vision, we can improve it to a degree that they can do activities they couldn’t do before, like playing outside at night. They gain greater visual clarity of edges on objects, so they can draw and enjoy picture books, and play with toys like puzzles and Legos.”

The breakthrough one-time treatment replaces a defective gene called RPE65 located in the retina, the membrane at the back of the eye that detects light and color, with a healthy copy made from artificial DNA, the equivalent of human DNA. RPE65 is responsible for producing a protein that makes light receptors work in the eye.

Of the seven hospitals nationwide originally approved to deliver this therapy to patients, CHLA was the only program with two full-time, dedicated pediatric retinal surgeons on site — Nagiel, and Thomas C. Lee, MD, director of The Vision Center at CHLA and associate professor of ophthalmology at the USC Roski Eye Institute. CHLA also is home to the Center for Personalized Medicine, where a laboratory certified by the Clinical Laboratory Improvement Amendments (CLIA) can do the necessary genetic testing for potential patients to determine if they have the defective RPE65 gene.

“We are pleased to be able to offer this therapy that can truly impact a patient’s quality of life and, potentially, help them see their future through ‘new eyes’,” said Lee.

CHLA has performed the procedure on nine children, as young as age three, and a handful of adults. While results have been less dramatic with adult patients — the inherited disease manifests itself early in childhood and gets worse over time, leading to total blindness — eyesight improvement is largely contingent on how far the condition has advanced. “For adults the clock has been ticking and cells have been dying over time,” explains Nagiel, an assistant professor of Ophthalmology at Keck School of Medicine of USC. “We want to save what they have but the treatment is allowing them to see and experience things they haven’t done before.”

About Children’s Hospital Los Angeles

Founded in 1901, Children’s Hospital Los Angeles is ranked the top children’s hospital in California and fifth in the nation for clinical excellence with its selection to the prestigious U.S. News & World Report Honor Roll of children’s hospitals. Clinical care is led by physicians who are faculty members of the Keck School of Medicine of USC through an affiliation dating from 1932. The hospital also leads the largest pediatric residency training program at a freestanding children’s hospital of its kind in the western United States. The hospital is home to The Saban Research Institute, one of the few centers in the world that focuses on discoveries that advance the clinical care of children. To learn more, follow us on Facebook, Instagram, LinkedIn and Twitter, visit our blog for families (CHLA.org/blog) or our research blog (ResearCHLABlog.org).

Contacts

Lorenzo Benet

CHLA Public Relations Director

e: lbenet@chla.usc.edu

o: 323-361-4823

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Business Wire

GEICO’s Fredericksburg, Virginia ‘Pioneers’ Reflect on 25 Years in the Stafford County Community

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FREDERICKSBURG, Va.–(BUSINESS WIRE)–#Fredericksburg–Time flies at a company you love. Just ask Angela Cooke; she is one of the “pioneer” associates who was there when GEICO’s Fredericksburg Regional Office opened in 1994.


“I look back at that time and we were all in it together—one team,” she remembers. “I’m really proud and sentimental about it.”

The 25th anniversary of the opening of the Fredericksburg Regional Office has opened a floodgate of memories for other pioneers as well. Past and current associates from the first “pioneer” group took a look back at how much the company and the office have grown while still retaining its familial atmosphere.

“The expectation was that this would be the model for all GEICO offices around the country,” said former regional vice president John Izzo, who supervised the new office opening and celebrated a 38-year career with the company. “Helping establish our insurance operations here in Fredericksburg was one of the most rewarding experiences of my career,” he said.

Cooke, now a software engineering manager, remembers the cooperation and teamwork that were necessary to keep the office running smoothly and growing. “It was just a real sense of community and family when we first started.”

“Every day was definitely an adventure,” recalled Donna Stocking, who currently works as an HR representative.

The office had legendary picnics with dunk tanks and festive games, Field Day events which felt more like a family reunion than a corporate event, and holiday gatherings. That sense of camaraderie has existed since the company was founded in 1936 and helped GEICO grow into the second-largest auto insurer in the country, and the number one auto insurer in Virginia.

GEICO has a history of not only serving its customers, but also serving its local communities. Associates were—and continue to be—active in the community, volunteering their time and fundraising on behalf of hundreds of non-profit organizations.

“Fredericksburg associates have always been dedicated to helping in the community,” said current Regional Vice President Scott Markel, who was also part of that pioneer group. “Even back in the day, our associates were as committed to doing good works as they are to helping our customers.”

Over the past 25 years, GEICO’s Fredericksburg office and its associates donated more than $14 million to local charitable causes. Some notable items funded include handicapped-accessible playground, multiple busses and vans for summer camps, golf carts for law enforcement safe driving programs, child safety seat inspections and donations, and many other projects.

About GEICO

GEICO (Government Employees Insurance Company), the second-largest auto insurer in the U.S., was founded in 1936 and insures more than 28 million vehicles. For more than 80 years, the company has worked to make people’s lives better by protecting policyholders against unexpected events. As GEICO has grown, it has delivered money-saving coverage and outstanding customer service to policyholders through its investment in human resources and technology. GEICO is a member of the Berkshire Hathaway family of companies. GEICO also provides homeowners, renters, condo, flood, identity theft and term life coverages through non-affiliated insurance companies secured through the GEICO Insurance Agency, Inc. Commercial auto and personal umbrella coverages are also available. GEICO has a national workforce of 40,000 associates. GEICO sales representatives throughout the country are licensed insurance agents in order to help guide customers through coverage decisions. To make changes, report claims, print insurance cards and/or purchase additional products, policyholders can access their insurance policy here, connect via GEICO Mobile or by phone. Sales and service is also available at GEICO Local Offices. Visit www.geico.com for a quote or to learn more.

Contacts

GEICO Communications

gcorpcomm@geico.com

To view GEICO’s Blog: https://www.geico.com/more/

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Business Wire

PRICESMART 72 HOUR DEADLINE ALERT: Approximately 72 Hours Remain; Former Louisiana Attorney General and Kahn Swick & Foti, LLC Remind Investors With Losses in Excess of $100,000 of Deadline in Class Action Lawsuit Against PriceSmart, Inc. – PSMT

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NEW ORLEANS–(BUSINESS WIRE)–Kahn Swick & Foti, LLC (“KSF”) and KSF partner, the former Attorney General of Louisiana, Charles C. Foti, Jr., remind investors with large financial interests that they have only until July 22, 2019 to file lead plaintiff applications in a securities class action lawsuit against PriceSmart, Inc. (NasdaqGS: PSMT). Investor losses must relate to purchases of the Company’s securities between October 26, 2017 and October 25, 2018. This action is pending in the United States District Court for the Southern District of California.

What You May Do

If you purchased securities of PriceSmart and would like to discuss your legal rights and how this case might affect you and your right to recover for your economic loss, you may, without obligation or cost to you, contact KSF Managing Partner Lewis Kahn toll-free at 1-877-515-1850 or via email (lewis.kahn@ksfcounsel.com), or visit https://www.ksfcounsel.com/cases/nasdaqgs-psmt/ to learn more. If you wish to serve as a lead plaintiff in this class action by overseeing lead counsel with the goal of obtaining a fair and just resolution, you must request this position by application to the Court by July 22, 2019.

About the Lawsuit

On October 25, 2018, the Company disclosed disappointing operating results for the fourth quarter and year ended August 31, 2018, as well as the discovery of a “balance sheet misclassification” requiring the restatement of certain financial statements and the resignation of its Chief Executive Officer.

The case is Harari v. PriceSmart, Inc., et al, 19-cv-00958.

About Kahn Swick & Foti, LLC

KSF, whose partners include the former Louisiana Attorney General Charles C. Foti, Jr., is a law firm focused on securities, antitrust and consumer class actions, along with merger & acquisition and breach of fiduciary litigation against publicly traded companies on behalf of shareholders. The firm has offices in New York, California and Louisiana.

To learn more about KSF, you may visit www.ksfcounsel.com.

Contacts

Kahn Swick & Foti, LLC

Lewis Kahn, Managing Partner

lewis.kahn@ksfcounsel.com

1-877-515-1850

1100 Poydras St., Suite 3200

New Orleans, LA 70163

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Business Wire

INVESTIGATION ALERT: The Schall Law Firm Announces it is Investigating Claims Against Netflix, Inc. and Encourages Investors with Losses in Excess of $100,000 to Contact the Firm

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LOS ANGELES–(BUSINESS WIRE)–$NFLX #NFLXThe Schall Law Firm, a national shareholder rights litigation firm, announces that it is investigating claims on behalf of investors of Netflix, Inc. (“Netflix” or “the Company”) (NASDAQ: NFLX) for violations of §§10(b) and 20(a) of the Securities Exchange Act of 1934 and Rule 10b-5 promulgated thereunder by the U.S. Securities and Exchange Commission.

The investigation focuses on whether the Company issued false and/or misleading statements and/or failed to disclose information pertinent to investors. Netflix announced its second quarter 2019 earnings on July 17, 2019. During the Company’s earnings call, as well as in its shareholder letter, it was revealed that Netflix gained only 2.7 million new subscribers against a forecast of 5 million new subscribers. Based on this startling news, shares of Netflix dropped by more than 13% over the next two days.

If you are a shareholder who suffered a loss, click here to participate.

We also encourage you to contact Brian Schall of the Schall Law Firm, 1880 Century Park East, Suite 404, Los Angeles, CA 90067, at 424-303-1964, to discuss your rights free of charge. You can also reach us through the firm’s website at www.schallfirm.com, or by email at brian@schallfirm.com.

The class in this case has not yet been certified, and until certification occurs, you are not represented by an attorney. If you choose to take no action, you can remain an absent class member.

The Schall Law Firm represents investors around the world and specializes in securities class action lawsuits and shareholder rights litigation.

This press release may be considered Attorney Advertising in some jurisdictions under the applicable law and rules of ethics.

Contacts

The Schall Law Firm

Brian Schall, Esq.

310-301-3335

Cell: 424-303-1964

info@schallfirm.com

www.schallfirm.com

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